Welcome to the Kazak lab!
The central theme of the Kazak lab is the molecular control of mammalian energy metabolism and its influence on physiology. We use genetic and biochemical approaches to investigate the molecular determinants of obesity and obesity-associated disease, using cultured cells and genetically engineered mouse models. Our efforts are primarily focused on identifying the regulation and control of biochemical pathways in brown adipocytes that support thermogenesis. While adipocyte biology is home base for us, our current research interests also extend to cancer cell metabolism and immune regulation. We are located in the McIntyre Medical Sciences Building at the Goodman Cancer Research Centre and Department of Biochemistry at McGill University.
“A central lesson of science is that to understand complex issues (or even simple ones), we must try to free our minds of dogma and to guarantee the freedom to publish, to contradict, and to experiment. Arguments from authority are unacceptable.” Carl Sagan